KHSRP Antikörper (Middle Region)
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- Target Alle KHSRP Antikörper anzeigen
- KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KHSRP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- WEEYYKKQAQ VATGGGPGAP PGSQPDYSAA WAEYYRQQAA YYGQTPGPGG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KHSRP. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human KHSRP
- Top Product
- Discover our top product KHSRP Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 711 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Electrophilic tuning of the chemoprotective natural product sulforaphane." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 21, pp. 9590-5, (2010) (PubMed).
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Electrophilic tuning of the chemoprotective natural product sulforaphane." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 21, pp. 9590-5, (2010) (PubMed).
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- Target
- KHSRP (KH-Type Splicing Regulatory Protein (KHSRP))
- Andere Bezeichnung
- KHSRP (KHSRP Produkte)
- Synonyme
- FBP2 antikoerper, FUBP2 antikoerper, KSRP antikoerper, 6330409F21Rik antikoerper, Fbp2 antikoerper, Fubp2 antikoerper, Ksrp antikoerper, Marta1 antikoerper, KHSRP antikoerper, VgRBP71 antikoerper, fbp2 antikoerper, ksrp antikoerper, fubp2 antikoerper, fc94c12 antikoerper, wu:fb25b12 antikoerper, wu:fc10e10 antikoerper, wu:fc94c12 antikoerper, zgc:163038 antikoerper, khsrp-b antikoerper, KH-type splicing regulatory protein antikoerper, KH-type splicing regulatory protein L homeolog antikoerper, KH-type splicing regulatory protein S homeolog antikoerper, KHSRP antikoerper, Khsrp antikoerper, khsrp.L antikoerper, khsrp antikoerper, khsrp.S antikoerper
- Hintergrund
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KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking. It is part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. KHSRP mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE).It is also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Alias Symbols: FBP2, FUBP2, KSRP, MGC99676
Protein Interaction Partner: HUWE1, Bace1, UBC, STAU1, LGR4, MDM2, WWOX, SUZ12, EED, RNF2, NAP1L4, HNRNPD, GFPT1, GARS, APBB1, ALDH16A1, TARDBP, CD81, MPG, UBL4A, WHSC1, VCAM1, ITGA4, FN1, STRIP1, ASF1B, CPLX1, CIRBP, SUMO1, RAE1, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4B, CUL5, NEDD8, C
Protein Size: 711 - Molekulargewicht
- 73 kDa
- Gen-ID
- 8570
- NCBI Accession
- NM_003685, NP_003676
- UniProt
- Q92945
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