EIF4G3 Antikörper (Middle Region)

Produktnummer ABIN2778868

Produktdetails anti-EIF4G3 Antikörper

Target: EIF4G3 (Eukaryotic Translation Initiation Factor 4 gamma 3 (EIF4G3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4G3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MRGGSSKDLL DNQSQEEQRR EMLETVKQLT GGVDVERNST EAERNKTRES

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF4G3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EIF4G3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1585 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EIF4G3 Antikörper (ABIN2778868)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu EIF4G3

Target: EIF4G3 (Eukaryotic Translation Initiation Factor 4 gamma 3 (EIF4G3))

Andere Bezeichnung: EIF4G3 (EIF4G3 Produkte)

Hintergrund: EIF4G3 is probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. It is thought to be a functional homolog of EIF4G1.
Alias Symbols: eIF4GII, eIF4G 3, eIF-4G 3
Protein Interaction Partner: UBC, LGR4, TARDBP, ESR1, LIG4, EIF4G2, EIF4G1, EIF4A2, EIF4A1, SIRT7, VAV2, MKNK1, USP10, EIF3H, EIF3F, CAMK1, PABPC1, EIF4E,
Protein Size: 1585

Molekulargewicht: 174 kDa

Gen-ID: 8672

NCBI Accession: NM_003760, NP_003751

UniProt: O43432