Synaptojanin 1 Antikörper (N-Term)

Produktnummer ABIN2778875

Produktdetails anti-Synaptojanin 1 Antikörper

Target: Synaptojanin 1 (SYNJ1)

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Schwein, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synaptojanin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IDSSDEDRIS EVRKVLNSGN FYFAWSASGI SLDLSLNAHR SMQEQTTDNR

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SYNJ1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SYNJ1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1295 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Synaptojanin 1 Antikörper (ABIN2778875)

Thole, Vermeer, Zhang, Gadella, Nielsen: "Root hair defective4 encodes a phosphatidylinositol-4-phosphate phosphatase required for proper root hair development in Arabidopsis thaliana." in: The Plant cell, Vol. 20, Issue 2, pp. 381-95, (2008) (PubMed).

Details zu Synaptojanin 1

Target: Synaptojanin 1 (SYNJ1)

Andere Bezeichnung: SYNJ1 (SYNJ1 Produkte)

Synonyme: CG6562 antikoerper, Dmel\\CG6562 antikoerper, IPP antikoerper, Synj antikoerper, fb02f11 antikoerper, fi15a11 antikoerper, nrc antikoerper, wu:fb02f11 antikoerper, wu:fi15a11 antikoerper, SYNJ1 antikoerper, INPP5G antikoerper, A930006D20Rik antikoerper, AA675315 antikoerper, mKIAA0910 antikoerper, Synaptojanin antikoerper, synaptojanin 1 antikoerper, Synj antikoerper, synj1 antikoerper, SYNJ1 antikoerper, Synj1 antikoerper

Hintergrund: Synaptojanin 1 is a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking.Synaptojanin-1 is a phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) that has a role in clathrin-coated pit dynamics Perera et al. (2006) [PubMed 17158794].[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3383 AB020717.2 1-3383 3384-3539 AF009040.1 3318-3473 3540-4183 AF009039.1 3522-4165 4184-7039 AB020717.2 4142-6997
Alias Symbols: INPP5G
Protein Interaction Partner: UBC, GRB2, CLTC, CLTA, AP2M1, AP2A1, ITSN1, SH3KBP1, SH3GL1, AMPH, SH3GLB1, SORBS2, FNBP4, SH3BP1, EPS15, PACSIN3, PACSIN1, SH3GL2, SH3GL3, BIN1, EPHB2, CDK5, PPP3CA, PACSIN2,
Protein Size: 1295

Molekulargewicht: 143 kDa

Gen-ID: 8867

NCBI Accession: NM_203446, NP_982271

UniProt: O43426

Pathways: Inositol Metabolic Process, Synaptic Vesicle Exocytosis