SNRPA1 Antikörper (Middle Region)

Produktnummer ABIN2778901

Produktdetails anti-SNRPA1 Antikörper

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MPGQMPPAQP LSENPPNHIL FLTNLPEETN ELMLSMLFNQ FPGFKEVRLV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SNRPA. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SNRPA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 282 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SNRPA1 Antikörper (ABIN2778901)

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Details zu SNRPA1

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Andere Bezeichnung: SNRPA (SNRPA Produkte)

Hintergrund: SNRPA binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.
Alias Symbols: U1A, Mud1, U1-A
Protein Interaction Partner: LENG8, METTL13, RBMX, NDUFAF3, MTUS2, U2AF2, ENOX2, QKI, SNRPA1, SNRPA, SFPQ, TRIM27, RBM3, PTBP1, PCBP2, PCBP1, HNRNPK, GABPB1, CIRBP, UBC, LIN28B, LIN28A, RNF2, EZH2, SUZ12, EED, PRKDC, GIT1, WBP4, CDKN2A, SRPK2, SRPK3, C19orf43, TP63, SMAD5, IL7R, IFIT
Protein Size: 282

Molekulargewicht: 31 kDa

Gen-ID: 6626

NCBI Accession: NM_004596, NP_004587

UniProt: P09012