AIMP1 Antikörper (N-Term)

Produktnummer ABIN2778912

Produktdetails anti-AIMP1 Antikörper

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LLKEKAILQA TLREEKKLRV ENAKLKKEIE ELKQELIQAE IQNGVKQIPF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SCYE1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SCYE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 312 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AIMP1 Antikörper (ABIN2778912)

Tandle, Mazzanti, Alexander, Roberts, Libutti: "Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells." in: Cytokine, Vol. 30, Issue 6, pp. 347-58, (2005) (PubMed).

Details zu AIMP1

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Andere Bezeichnung: SCYE1 (AIMP1 Produkte)

Synonyme: EMAP2 antikoerper, EMAPII antikoerper, HLD3 antikoerper, SCYE1 antikoerper, p43 antikoerper, wu:fa95a05 antikoerper, zgc:154081 antikoerper, AIMP1 antikoerper, 9830137A06Rik antikoerper, AIMP1/p43 antikoerper, Emap2 antikoerper, Scye1 antikoerper, scye1 antikoerper, aminoacyl tRNA synthetase complex interacting multifunctional protein 1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog antikoerper, AIMP1 antikoerper, aimp1 antikoerper, Aimp1 antikoerper, aimp1.S antikoerper

Hintergrund: SCYE1 is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.The protein encoded by this gene is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.
Alias Symbols: p43, HLD3, EMAP2, SCYE1, EMAPII
Protein Interaction Partner: AIMP2, TSNAX, UBC, CCAR2, RPL36, EEF1E1, IQGAP1, VARS, RPLP0, RPL27A, RPL23A, RPL21, RPL17, RPL15, RPL13, RPL7A, RARS, QARS, PTBP1, PSMC6, MARS, KARS, IARS, DNAJA1, EIF4G1, EIF2S3, EIF2S1, DARS, PAN2, gag, HSP90B1, MAPK8, LARS, EPRS, APP, COPS5, CUL1, PSM
Protein Size: 312

Molekulargewicht: 34 kDa

Gen-ID: 9255

NCBI Accession: NM_004757, NP_004748

UniProt: Q12904