EIF4E2 Antikörper (N-Term)

Produktnummer ABIN2778915

Produktdetails anti-EIF4E2 Antikörper

Target: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4E2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KDDDSGDHDQ NEENSTQKDG EKEKTERDKN QSSSKRKAVV PGPAEHPLQY

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF4E2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4E2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 245 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EIF4E2 Antikörper (ABIN2778915)

Tee, Tee, Blenis: "Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1." in: FEBS letters, Vol. 564, Issue 1-2, pp. 58-62, (2004) (PubMed).

Details zu EIF4E2

Target: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Andere Bezeichnung: EIF4E2 (EIF4E2 Produkte)

Synonyme: 4E-LP antikoerper, 4EHP antikoerper, EIF4EL3 antikoerper, IF4e antikoerper, Eif4el3 antikoerper, EIF4E2 antikoerper, id:ibd1007 antikoerper, zgc:110542 antikoerper, zgc:158544 antikoerper, MGC115622 antikoerper, 2700069E09Rik antikoerper, AI036339 antikoerper, AV129531 antikoerper, D0H0S6743E antikoerper, eukaryotic translation initiation factor 4E family member 2 antikoerper, eukaryotic translation initiation factor 4E member 2 antikoerper, eukaryotic translation initiation factor 4E family member 2 L homeolog antikoerper, EIF4E2 antikoerper, Eif4e2 antikoerper, eif4e2 antikoerper, eif4e2.L antikoerper

Hintergrund: EIF4E2 belongs to the eukaryotic initiation factor 4E family. It recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Alias Symbols: 4EHP, IF4e, 4E-LP, EIF4EL3
Protein Interaction Partner: USHBP1, CARD9, PRDM14, HOMEZ, TRIM54, NECAB2, ADAMTSL4, AMOTL2, SPAG5, SPRY2, HUWE1, TMCC2, MAGED1, TCF4, TADA2A, TRIM27, REL, MYOG, KRT31, KRT19, KRT13, CDR2, AES, MAPRE3, NOTCH2NL, KRTAP10-8, KRTAP10-5, KRTAP10-9, ZBTB9, SPERT, USP54, MIPOL1, KRT40, UBX
Protein Size: 245

Molekulargewicht: 27 kDa

Gen-ID: 9470

NCBI Accession: NM_004846, NP_004837

UniProt: O60573

Pathways: SARS-CoV-2 Protein Interaktom