HNRPDL Antikörper (C-Term)

Produktnummer ABIN2778938

Produktdetails anti-HNRPDL Antikörper

Target: HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRPDL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YSGYGGYDYT GYNYGNYGYG QGYADYSGQQ STYGKASRGG GNHQNNYQPY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRPDL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPDL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 420 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNRPDL Antikörper (ABIN2778938)

Li, Johansson, Glahder, Mossberg, Schwartz: "Suppression of HPV-16 late L1 5'-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs." in: Nucleic acids research, Vol. 41, Issue 22, pp. 10488-508, (2013) (PubMed).

Anderson, Lin, Xiao, Stoilov, Burge, Black: "The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B." in: RNA (New York, N.Y.), Vol. 18, Issue 5, pp. 1041-9, (2012) (PubMed).

Details zu HNRPDL

Target: HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

Andere Bezeichnung: HNRPDL (HNRPDL Produkte)

Synonyme: wu:fa11d08 antikoerper, zgc:66169 antikoerper, hnRNP DL antikoerper, Hnrpdl antikoerper, AA407431 antikoerper, AA959857 antikoerper, D5Ertd650e antikoerper, D5Wsu145e antikoerper, JKTBP antikoerper, hnRNP-DL antikoerper, hnRNP antikoerper, hnrpdl antikoerper, hnrpdl-a antikoerper, jktbp antikoerper, jktbp2 antikoerper, laauf1 antikoerper, HNRNP antikoerper, HNRPDL antikoerper, JKTBP2 antikoerper, laAUF1 antikoerper, hnRNP D-like B antikoerper, hnRNP DL-B antikoerper, hnrnpdl-b antikoerper, hnrpdl-b antikoerper, heterogeneous nuclear ribonucleoprotein D-like antikoerper, heterogeneous nuclear ribonucleoprotein D like antikoerper, heterogeneous nuclear ribonucleoprotein D like L homeolog antikoerper, heterogeneous nuclear ribonucleoprotein D like S homeolog antikoerper, hnrpdl antikoerper, HNRNPDL antikoerper, Hnrnpdl antikoerper, hnrnpdl.L antikoerper, LOC100351670 antikoerper, LOC101120922 antikoerper, hnrnpdl.S antikoerper

Hintergrund: HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPDL has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein is similar to its family member HNRPD.
Alias Symbols: HNRNP, JKTBP, JKTBP2, laAUF1, HNRPDL
Protein Interaction Partner: SPRTN, SUMO2, SUMO3, UBC, RPA3, RPA2, RPA1, ERG, EED, RNF2, rev, PARK2, FBXO6, TARDBP, HMGA1, ITGA4, IL7R, IFIT3, IFIT2, FN1, CSNK2A1, BARD1, EEF2, EEF1A1, DDX3X, ATP6V1B1, HNRNPA3, WIPF2, RMDN3, MRPS16, UBE2S, LSM14A, RPL36, U2AF2, HNRNPUL1, HNRNPA0, HNR
Protein Size: 420

Molekulargewicht: 46 kDa

Gen-ID: 9987

NCBI Accession: NM_005463, NP_005454

UniProt: O14979