KARS Antikörper (C-Term)

Produktnummer ABIN2778941

Produktdetails anti-KARS Antikörper

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV

Homologie: Cow: 92%, Guinea Pig: 85%, Horse: 88%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against KARS. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KARS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 597 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KARS

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Andere Bezeichnung: KARS (KARS Produkte)

Hintergrund: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Alias Symbols: KRS, KARS2, CMTRIB
Protein Interaction Partner: AIMP2, SUMO2, SUMO3, MDM2, UBC, SUMO1, NEDD8, STAT1, SSB, RPL21, RPL19, RPL17, NAP1L4, HSPA4, GPX1, CARS, APEH, CAND1, RANBP6, RPL36, JMJD6, NUDC, IPO7, AIMP1, SH3RF2, FBXO6, vpr, MSK1, gag, FN1, TRMT1, MRPS18B, UBE2S, CCT8, EEF1E1, VBP1, UBA1, RARS, QARS
Protein Size: 597

Molekulargewicht: 66 kDa

Gen-ID: 3735

NCBI Accession: NM_005548, NP_005539

UniProt: Q15046