HNRNPR Antikörper (N-Term)

Produktnummer ABIN2778950

Produktdetails anti-HNRNPR Antikörper

Target: HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ANQVNGNAVQ LKEEEEPMDT SSVTHTEHYK TLIEAGLPQK VAERLDEIFQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRNPR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRNPR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 633 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNRNPR Antikörper (ABIN2778950)

Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).

Details zu HNRNPR

Target: HNRNPR (Heterogeneous Nuclear Ribonucleoprotein R (HNRNPR))

Andere Bezeichnung: HNRNPR (HNRNPR Produkte)

Synonyme: hnrpr antikoerper, wu:fb97a09 antikoerper, wu:fe01h03 antikoerper, zgc:56523 antikoerper, HNRPR antikoerper, hnRNP R antikoerper, hnRNP-R antikoerper, 2610003J05Rik antikoerper, 2610528B01Rik antikoerper, Hnrpr antikoerper, heterogeneous nuclear ribonucleoprotein R antikoerper, hnrnpr antikoerper, HNRNPR antikoerper, Hnrnpr antikoerper

Hintergrund: HNRNPR belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: FLJ25714, HNRPR, hnRNP-R, hnRNP R
Protein Interaction Partner: PRMT1, KHDRBS2, CEP250, SUMO2, IVNS1ABP, STAU1, UBC, MDM2, WWOX, ZBTB1, RPA3, RPA2, RPA1, RNF2, EED, rev, PPP4R1, MTA2, CCDC6, EHBP1L1, RABEP2, BRCC3, SMEK1, LSM8, LARP7, GAPVD1, CD2AP, WDHD1, SF3A1, TRIM28, HDAC1, NR3C1, POLR2C, POLR2A, MAP4, PARK2, SRPK
Protein Size: 633

Molekulargewicht: 71 kDa

Gen-ID: 10236

NCBI Accession: NM_005826, NP_005817

UniProt: O43390