SF3B4 Antikörper (N-Term)
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- Target Alle SF3B4 Antikörper anzeigen
- SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd, Saccharomyces cerevisiae, Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SF3B4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- QDATVYVGGL DEKVSEPLLW ELFLQAGPVV NTHMPKDRVT GQHQGYGFVE
- Homologie
- Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SF3B4. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B4
- Top Product
- Discover our top product SF3B4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 424 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
- Andere Bezeichnung
- SF3B4 (SF3B4 Produkte)
- Synonyme
- chunp6902 antikoerper, fb36a04 antikoerper, wu:fb36a04 antikoerper, 49kDa antikoerper, SF3b49 antikoerper, SF3b50 antikoerper, Sap49 antikoerper, spx antikoerper, AFD1 antikoerper, Hsh49 antikoerper, SAP49 antikoerper, Splicing factor 3B subunit 4 antikoerper, splicing factor 3b, subunit 4 antikoerper, splicing factor 3b subunit 4 S homeolog antikoerper, splicing factor 3b subunit 4 antikoerper, sap-49 antikoerper, sf3b4 antikoerper, Sf3b4 antikoerper, sf3b4.S antikoerper, SF3B4 antikoerper
- Hintergrund
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SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Alias Symbols: Hsh49, SAP49, SF3b49
Protein Interaction Partner: NCK2, METTL17, ZCCHC10, UBASH3A, NUB1, HSPB7, PPP1R16B, SS18L1, HNRNPUL1, SF3B2, BAIAP2, SEC24D, FAM115A, RBM39, BAG3, CWF19L2, MAPK9, FUS, FRK, FKBP1A, STAU1, UBC, SUMO1, SUZ12, RNF2, PRPF40A, WBP4, APBB1, SRPK3, DDX42, PRPF8, CHERP, DDX17, BCAS2, EFTUD2
Protein Size: 424 - Molekulargewicht
- 47 kDa
- Gen-ID
- 10262
- NCBI Accession
- NM_005850, NP_005841
- UniProt
- Q15427
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