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SF3B4 Antikörper (N-Term)

SF3B4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd, Saccharomyces cerevisiae, Ziege WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778952
  • Target Alle SF3B4 Antikörper anzeigen
    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
    Bindungsspezifität
    • 9
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 41
    • 20
    • 19
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd, Saccharomyces cerevisiae, Ziege
    Wirt
    • 36
    • 5
    • 1
    Kaninchen
    Klonalität
    • 37
    • 5
    Polyklonal
    Konjugat
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SF3B4 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 24
    • 10
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    QDATVYVGGL DEKVSEPLLW ELFLQAGPVV NTHMPKDRVT GQHQGYGFVE
    Homologie
    Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SF3B4. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B4
    Top Product
    Discover our top product SF3B4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 424 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
    Andere Bezeichnung
    SF3B4 (SF3B4 Produkte)
    Synonyme
    chunp6902 antikoerper, fb36a04 antikoerper, wu:fb36a04 antikoerper, 49kDa antikoerper, SF3b49 antikoerper, SF3b50 antikoerper, Sap49 antikoerper, spx antikoerper, AFD1 antikoerper, Hsh49 antikoerper, SAP49 antikoerper, Splicing factor 3B subunit 4 antikoerper, splicing factor 3b, subunit 4 antikoerper, splicing factor 3b subunit 4 S homeolog antikoerper, splicing factor 3b subunit 4 antikoerper, sap-49 antikoerper, sf3b4 antikoerper, Sf3b4 antikoerper, sf3b4.S antikoerper, SF3B4 antikoerper
    Hintergrund
    SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
    Alias Symbols: Hsh49, SAP49, SF3b49
    Protein Interaction Partner: NCK2, METTL17, ZCCHC10, UBASH3A, NUB1, HSPB7, PPP1R16B, SS18L1, HNRNPUL1, SF3B2, BAIAP2, SEC24D, FAM115A, RBM39, BAG3, CWF19L2, MAPK9, FUS, FRK, FKBP1A, STAU1, UBC, SUMO1, SUZ12, RNF2, PRPF40A, WBP4, APBB1, SRPK3, DDX42, PRPF8, CHERP, DDX17, BCAS2, EFTUD2
    Protein Size: 424
    Molekulargewicht
    47 kDa
    Gen-ID
    10262
    NCBI Accession
    NM_005850, NP_005841
    UniProt
    Q15427
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