SF3B4 Antikörper (N-Term)

Produktnummer ABIN2778952

Der Kaninchen Polyklonal Anti-SF3B4-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SF3B4 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Saccharomyces cerevisiae, Pferd und Ziege zu detektieren.

Kurzübersicht für SF3B4 Antikörper (N-Term) (ABIN2778952)

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen, Saccharomyces cerevisiae, Pferd, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SF3B4 Antikörper

Bindungsspezifität: N-Term

Sequenz: QDATVYVGGL DEKVSEPLLW ELFLQAGPVV NTHMPKDRVT GQHQGYGFVE

Homologie: Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SF3B4. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 424 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SF3B4

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Andere Bezeichnung: SF3B4

Hintergrund: SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Alias Symbols: Hsh49, SAP49, SF3b49
Protein Interaction Partner: NCK2, METTL17, ZCCHC10, UBASH3A, NUB1, HSPB7, PPP1R16B, SS18L1, HNRNPUL1, SF3B2, BAIAP2, SEC24D, FAM115A, RBM39, BAG3, CWF19L2, MAPK9, FUS, FRK, FKBP1A, STAU1, UBC, SUMO1, SUZ12, RNF2, PRPF40A, WBP4, APBB1, SRPK3, DDX42, PRPF8, CHERP, DDX17, BCAS2, EFTUD2
Protein Size: 424

Molekulargewicht: 47 kDa

Gen-ID: 10262

NCBI Accession: NM_005850, NP_005841

UniProt: Q15427