SMNDC1 Antikörper (Middle Region)

Produktnummer ABIN2778955

Produktdetails anti-SMNDC1 Antikörper

Target: SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Ziege, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMNDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QFNNRAYSKN KKGQVKRSIF ASPESVTGKV GVGTCGIADK PMTQYQDTSK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SMNDC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMNDC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 238 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMNDC1

Target: SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))

Andere Bezeichnung: SMNDC1 (SMNDC1 Produkte)

Synonyme: smnr antikoerper, spf30 antikoerper, SMNDC1 antikoerper, SMNR antikoerper, SPF30 antikoerper, TDRD16C antikoerper, wu:fb37h07 antikoerper, wu:fc23a07 antikoerper, 2410004J23Rik antikoerper, 4933440I19Rik antikoerper, survival motor neuron domain containing 1 antikoerper, smndc1 antikoerper, SMNDC1 antikoerper, Bm1_41545 antikoerper, Smndc1 antikoerper

Hintergrund: This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Alias Symbols: SMNR, SPF30
Protein Interaction Partner: UBC, PRPF3, SF3B5, SND1, CUL3, SF3A2, ELAVL1, HIST3H3, mad2, KPNB1, SNRNP200, SNRPB, CDK5RAP3, PPAN, TSR1, RNMTL1, SF3B1, SF3B3, SF3B2, SF3A3, SF3B4, DDX21, RUVBL1, RPL3, FDFT1, EWSR1,
Protein Size: 238

Molekulargewicht: 27 kDa

Gen-ID: 10285

NCBI Accession: NM_005871, NP_005862

UniProt: O75940