HNRNPM Antikörper (N-Term)

Produktnummer ABIN2778962

Produktdetails anti-HNRNPM Antikörper

Target: HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ATEIKMEEES GAPGVPSGNG APGPKGEGER PAQNEKRKEK NIKRGGNRFE

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRPM. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPM

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 691 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNRNPM Antikörper (ABIN2778962)

Huelga, Vu, Arnold, Liang, Liu, Yan, Donohue, Shiue, Hoon, Brenner, Ares, Yeo: "Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins." in: Cell reports, Vol. 1, Issue 2, pp. 167-78, (2012) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu HNRNPM

Target: HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))

Andere Bezeichnung: HNRPM (HNRNPM Produkte)

Synonyme: HNRPM antikoerper, si:ch211-197g15.1 antikoerper, wu:fa10g07 antikoerper, wu:fa98b02 antikoerper, hnrpm antikoerper, CG9373 antikoerper, Dmel\\CG9373 antikoerper, Hrp59 antikoerper, cg9373 antikoerper, hnRNP M antikoerper, hrp59 antikoerper, p75 antikoerper, CEAR antikoerper, HNRNPM4 antikoerper, HNRPM4 antikoerper, HTGR1 antikoerper, NAGR1 antikoerper, 2610023M21Rik antikoerper, AA409009 antikoerper, Hnrpm antikoerper, mKIAA4193 antikoerper, Hnrpm4 antikoerper, heterogeneous nuclear ribonucleoprotein M antikoerper, Heterogeneous nuclear ribonucleoprotein M antikoerper, rumpelstiltskin antikoerper, HNRNPM antikoerper, hnrnpm antikoerper, hnrpm antikoerper, rump antikoerper, Hnrnpm antikoerper

Hintergrund: HNRPM belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPM has three repeats of quasi-RRM domains that bind to RNAs. HNRPM also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated.
Alias Symbols: DKFZp547H118, HNRNPM, HNRNPM4, HNRPM4, HTGR1, NAGR1, CEAR, HNRPM, hnRNP M
Protein Interaction Partner: UBC, TP53, AKAP9, TEKT4, GMCL1P1, LMO2, HNRNPF, SUMO2, SUMO3, CEP250, MDM2, HAUS1, CDC37, IVNS1ABP, STAU1, SUMO1, RPA3, RPA2, RPA1, EED, rev, RTCB, RPL26L1, RFC4, PSMB8, NMT1, MRE11A, FLII, IGF2BP3, EIF2B2, EIF2B3, RPL27, RPL19, DHX9, DDX1, ABCF1, PARK2,
Protein Size: 691

Molekulargewicht: 73 kDa

Gen-ID: 4670

NCBI Accession: NM_031203, NP_112480

UniProt: P52272