SFRS6 Antikörper (Middle Region)

Produktnummer ABIN2778972

Produktdetails anti-SFRS6 Antikörper

Target: SFRS6 (SRSF6) (serine/arginine-Rich Splicing Factor 6 (SRSF6))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Pferd, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KERTNEGVIE FRSYSDMKRA LDKLDGTEIN GRNIRLIEDK PRTSHRRSYS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SFRS6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SFRS6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 344 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SFRS6 Antikörper (ABIN2778972)

Gautrey, Tyson-Capper: "Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells." in: PLoS ONE, Vol. 7, Issue 12, pp. e51497, (2013) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu SFRS6

Target: SFRS6 (SRSF6) (serine/arginine-Rich Splicing Factor 6 (SRSF6))

Andere Bezeichnung: SFRS6 (SRSF6 Produkte)

Hintergrund: SFRS6 is involved in mRNA splicing and may play a role in the determination of alternative splicing. It belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: B52, MGC5045, SRP55, SFRS6
Protein Interaction Partner: LUC7L2, TP53, MDM2, ASB18, SUZ12, EED, RPL24, SRPK2, SRPK1, SRPK3, TARDBP, YWHAE, PAN2, TOE1, SF3B4, RBM10, UBC, TRA2B, EIF4A3, MAGOH, ESR1, BARD1, SRSF10, APP, CAND1, COPS5, SRRM1, CUL1, CUL2, TERF2, TERF1, HNRNPA1, SF3A2, ELAVL1, SREK1, AI837181, CLK1,
Protein Size: 344

Molekulargewicht: 39 kDa

Gen-ID: 6431

NCBI Accession: NM_006275, NP_006266

UniProt: Q13247

Pathways: Ribonucleoprotein Complex Subunit Organization