RBM14 Antikörper (N-Term)

Produktnummer ABIN310058

Produktdetails anti-RBM14 Antikörper

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YAFVHMEKEA DAKAAIAQLN GKEVKGKRIN VELSTKGQKK GPGLAVQSGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RBM14. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM14

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 669 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RBM14 Antikörper (ABIN310058)

Sui, Yang, Xiong, Zhang, Blanchard, Peiper, Dynan, Tuan, Ko: "Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers." in: Oncogene, Vol. 26, Issue 6, pp. 822-35, (2007) (PubMed).

Details zu RBM14

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Andere Bezeichnung: RBM14 (RBM14 Produkte)

Hintergrund: RBM14 contains 2 RRM (RNA recognition motif) domains. Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
Alias Symbols: COAA, DKFZp779J0927, SIP, SYTIP1, PSP2, TMEM137
Protein Interaction Partner: UBC, SUMO2, SUMO3, CEP250, DROSHA, MDM2, SMURF2, RPA3, RPA2, RPA1, EZH2, BMI1, RNF2, SUZ12, EED, MAPK15, CDK15, CDK14, HDAC9, HDAC11, WHSC1, VCAM1, TRAF3, ITGA4, FN1, ESR1, ZC3H18, FTSJ3, RBM25, TRMT112, HP1BP3, PRPF19, RBMX, RSL1D1, PRPF6, HNRNPH1, RCC1,
Protein Size: 669

Molekulargewicht: 69 kDa

Gen-ID: 10432

NCBI Accession: NM_006328, NP_006319

UniProt: Q96PK6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway