EMG1 Antikörper (N-Term)

Produktnummer ABIN2778974

Produktdetails anti-EMG1 Antikörper

Target: EMG1 (EMG1 Nucleolar Protein Homolog (EMG1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EMG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SLETVKVGKT YELLNCDKHK SILLKNGRDP GEARPDITHQ SLLMLMDSPL

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against EMG1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EMG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 244 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EMG1 Antikörper (ABIN2778974)

Armistead, Khatkar, Meyer, Mark, Patel, Coghlan, Lamont, Liu, Wiechert, Cattini, Koetter, Wrogemann, Greenberg, Entian, Zelinski, Triggs-Raine: "Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome." in: American journal of human genetics, Vol. 84, Issue 6, pp. 728-39, (2009) (PubMed).

Details zu EMG1

Target: EMG1 (EMG1 Nucleolar Protein Homolog (EMG1))

Andere Bezeichnung: EMG1 (EMG1 Produkte)

Synonyme: C2F antikoerper, Grcc2f antikoerper, NEP1 antikoerper, C2f antikoerper, EMG1, N1-specific pseudouridine methyltransferase antikoerper, EMG1 N1-specific pseudouridine methyltransferase antikoerper, EMG1 antikoerper, Emg1 antikoerper

Hintergrund: EMG1 involved in 40S ribosomal subunit biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing.
Alias Symbols: C2F, NEP1, Grcc2f
Protein Interaction Partner: FAM74A4, UBC, RPA3, RPA2, RPA1, EED, rev, HECW2, IL7R, FN1, BYSL, APP, NEDD8, SLC25A38, NAT6, PSMB7, KHDRBS1, PSME1, HIVEP1, CTSE, ANXA3,
Protein Size: 244

Molekulargewicht: 27 kDa

Gen-ID: 10436

NCBI Accession: NM_006331, NP_006322

UniProt: Q92979