PRPF8 Antikörper (N-Term)

Produktnummer ABIN2778986

Produktdetails anti-PRPF8 Antikörper

Target: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRPF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SHRHSVKSQE PLPDDDEEFE LPEFVEPFLK DTPLYTDNTA NGIALLWAPR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRPF8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2335 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PRPF8

Target: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Andere Bezeichnung: PRPF8 (PRPF8 Produkte)

Synonyme: id:ibd1257 antikoerper, ik:tdsubc_2a9 antikoerper, im:7141966 antikoerper, tdsubc_2a9 antikoerper, wu:fb37c02 antikoerper, wu:fb73e06 antikoerper, xx:tdsubc_2a9 antikoerper, zgc:56504 antikoerper, hprp8 antikoerper, prp-8 antikoerper, prp8 antikoerper, prpc8 antikoerper, rp13 antikoerper, HPRP8 antikoerper, PRP8 antikoerper, PRPC8 antikoerper, RP13 antikoerper, SNRNP220 antikoerper, AU019467 antikoerper, D11Bwg0410e antikoerper, DBF3/PRP8 antikoerper, Prp8 antikoerper, Sfprp8l antikoerper, pre-mRNA processing factor 8 antikoerper, pre-mRNA processing factor 8 S homeolog antikoerper, Prpf8 antikoerper, prpf8 antikoerper, prpf8.S antikoerper, PRPF8 antikoerper

Hintergrund: Pre-mRNA splicing occurs in 2 sequential transesterification steps. PRPF8 is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. The gene encoding PRPF8 is a candidate gene for autosomal dominant retinitis pigmentosa.Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HPRP8, PRP8, PRPC8, RP13
Protein Interaction Partner: SNRNP200, PRPF8, EFTUD2, UBC, CDKN1A, SUMO2, SUMO3, STAU1, LGR4, NEDD8, ERG, ASB15, WWOX, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, rev, PIN1, NEDD4, FBXO6, PRPF4B, UBD, IGSF8, ICAM1, SND1, SF3B2, SLU7, ZNF830, WDR83, PRPF19, GPKOW, FN1, BCAS2, SF3B4, RBM5, VCA
Protein Size: 2335

Molekulargewicht: 273 kDa

Gen-ID: 10594

NCBI Accession: NM_006445, NP_006436

UniProt: Q6P2Q9