KHDRBS1 Antikörper (N-Term)
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- Target Alle KHDRBS1 Antikörper anzeigen
- KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KHDRBS1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- LPELMAEKDS LDPSFTHAMQ LLTAEIEKIQ KGDSKKDDEE NYLDLFSHKN
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KHDRBS1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human KHDRBS1
- Top Product
- Discover our top product KHDRBS1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 443 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))
- Andere Bezeichnung
- KHDRBS1 (KHDRBS1 Produkte)
- Synonyme
- Sam68 antikoerper, p62 antikoerper, p68 antikoerper, fj90g10 antikoerper, khdrbs1 antikoerper, wu:fa18g12 antikoerper, wu:fa56c01 antikoerper, wu:fc91b01 antikoerper, wu:fj90g10 antikoerper, zgc:113899 antikoerper, KHDRBS1 antikoerper, P62 antikoerper, khdrbs1l antikoerper, sb:cb97 antikoerper, wu:fb07d11 antikoerper, wu:fi43c05 antikoerper, zgc:85948 antikoerper, KH RNA binding domain containing, signal transduction associated 1 antikoerper, KH domain containing, RNA binding, signal transduction associated 1a antikoerper, KH domain containing, RNA binding, signal transduction associated 1 antikoerper, KH domain containing, RNA binding, signal transduction associated 1 S homeolog antikoerper, KH domain containing, RNA binding, signal transduction associated 1b antikoerper, KHDRBS1 antikoerper, khdrbs1a antikoerper, khdrbs1 antikoerper, Khdrbs1 antikoerper, khdrbs1.S antikoerper, khdrbs1b antikoerper
- Hintergrund
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KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, KHDRBS1 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. KHDRBS1 play a role in G2-M progression in the cell cycle. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. KHDRBS1 also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
Alias Symbols: FLJ34027, Sam68, p62, p68
Protein Interaction Partner: UBC, LGR4, DROSHA, RPA3, RPA2, RPA1, RNF2, EZH2, BMI1, SUZ12, rev, APBB1, GAS7, WBP4, RASA1, SRC, CSK, PLCG1, PIK3R1, IRS1, CD81, TNFRSF1A, KHDRBS3, GPHN, RBM7, PIK3R3, HNRNPK, GRB2, EFEMP1, DHX9, DDX5, CRKL, CIRBP, ACTB, AZIN1, RBMX, AGO1, POT1, RBFOX2,
Protein Size: 443 - Molekulargewicht
- 48 kDa
- Gen-ID
- 10657
- NCBI Accession
- NM_006559, NP_006550
- UniProt
- Q07666
- Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
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