FARS2 Antikörper (N-Term)

Produktnummer ABIN2779002

Produktdetails anti-FARS2 Antikörper

Target: FARS2 (Phenylalanine-tRNA Synthetase 2 (Mitochondrial) (FARS2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Pferd, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FARS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VELLGKSYPQ DDHSNLTRKV LTRVGRNLHN QQHHPLWLIK ERVKEHFYKQ

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 85%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FARS2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FARS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 451 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FARS2

Target: FARS2 (Phenylalanine-tRNA Synthetase 2 (Mitochondrial) (FARS2))

Andere Bezeichnung: FARS2 (FARS2 Produkte)

Synonyme: 2810431B21Rik antikoerper, 6720478K01Rik antikoerper, Fars1 antikoerper, COXPD14 antikoerper, FARS1 antikoerper, HSPC320 antikoerper, PheRS antikoerper, dJ520B18.2 antikoerper, phenylalanine-tRNA synthetase 2 (mitochondrial) antikoerper, phenylalanyl-tRNA synthetase 2, mitochondrial antikoerper, Fars2 antikoerper, FARS2 antikoerper

Hintergrund: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS2 is a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS1 encodes a mitochondrially-located phenylalanine-tRNA synthetase (PheRS) which consists of a single polypeptide chain unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and the eukaryotic cytoplasm.
Alias Symbols: FARS1, HSPC320, PheRS, dJ520B18.2
Protein Interaction Partner: TRIM27, KRT31, KRT13, RCBTB2, NOTCH2NL, KRTAP10-3, KRTAP10-5, KRTAP10-9, KRTAP10-7, KRT40, CMTM5, HMBOX1, TRIM54, AGTRAP, ADAMTSL4, APPL1, IKZF3, MID2, CALCOCO2, STX11, MKRN3, TFCP2, TADA2A, SUMO1, UBC, NEDD8, CUL3, ISG15, ICT1, USP45, G3BP2,
Protein Size: 451

Molekulargewicht: 50 kDa

Gen-ID: 10667

NCBI Accession: NM_006567, NP_006558

UniProt: O95363