HNRNPA0 Antikörper (Middle Region)

Produktnummer ABIN2779011

Produktdetails anti-HNRNPA0 Antikörper

Target: HNRNPA0 (Heterogeneous Nuclear Ribonucleoprotein A0 (HNRNPA0))

Bindungsspezifität: Middle Region

Reaktivität: Human, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPA0 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Sequenz: KAAVVKFHPI QGHRVEVKKA VPKEDIYSGG GGGGSRSSRG GRGGRGRGGG

Homologie: Cow: 93%, Dog: 93%, Human: 100%, Pig: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRPA0. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HNRPA0

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 305 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HNRNPA0

Target: HNRNPA0 (Heterogeneous Nuclear Ribonucleoprotein A0 (HNRNPA0))

Andere Bezeichnung: HNRPA0 (HNRNPA0 Produkte)

Hintergrund: HNRPA0 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.
Alias Symbols: HNRPA0
Protein Interaction Partner: UBC, SUMO2, SUMO3, STAU1, RPA3, RPA2, RPA1, EED, RNF2, DYNC1LI1, PSMD13, PSMD12, PSMD8, MAP2, DYNC1I2, DHX9, ABCF1, RPS27, TARDBP, CSF2, NPM1, LMNA, AICDA, MAPKAPK2, GADD45A, U2AF2, VCAM1, SRSF1, NKX3-1, MTNR1A, ITGA4, IL7R, HNRNPK, HNRNPH3, HNRNPH2, HNRN
Protein Size: 305

Molekulargewicht: 34 kDa

Gen-ID: 10949

NCBI Accession: NM_006805, NP_006796

UniProt: Q13151