EIF2D Antikörper (Middle Region)

Produktnummer ABIN2779012

Produktdetails anti-EIF2D Antikörper

Target: EIF2D (Eukaryotic Translation Initiation Factor 2D (EIF2D))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KVTVVRNLEA YGLDPYSVAA ILQQRCQAST TVNPAPGAKD SLQVQIQGNQ

Homologie: Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against LGTN. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LGTN

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 584 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF2D

Target: EIF2D (Eukaryotic Translation Initiation Factor 2D (EIF2D))

Andere Bezeichnung: LGTN (EIF2D Produkte)

Hintergrund: LGTN is a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively.This gene encodes a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligatin mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively.
Alias Symbols: HCA56, LGTN
Protein Interaction Partner: UBC, AICDA, EIF1B, EIF1, HARS, DHX15, CUL3, HEXB, ACHE, RAD51,
Protein Size: 584

Molekulargewicht: 65 kDa

Gen-ID: 1939

NCBI Accession: NM_006893, NP_008824

UniProt: P41214