RBMXL2 Antikörper (Middle Region)

Produktnummer ABIN2779064

Produktdetails anti-RBMXL2 Antikörper

Target: RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Kaninchen, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBMXL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSRDGYSSRD YREPRGFAPS PGEYTHRDYG HSSVRDDCPL RGYSDRDGYG

Homologie: Cow: 85%, Dog: 77%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against RBMXL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBMXL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 392 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RBMXL2

Target: RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))

Andere Bezeichnung: RBMXL2 (RBMXL2 Produkte)

Synonyme: HNRNPG-T antikoerper, HNRNPGT antikoerper, HNRPGT antikoerper, 1700012H05Rik antikoerper, Hnrnpg-t antikoerper, RBMX antikoerper, hnRNP G-T antikoerper, RNA binding motif protein, X-linked like 2 antikoerper, RNA binding motif protein, X-linked-like 2 antikoerper, RBMXL2 antikoerper, Rbmxl2 antikoerper

Hintergrund: The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c
Alias Symbols: HNRNPG-T, HNRPGT, HNRNPGT
Protein Interaction Partner: UBC, RABGGTA, FDXACB1, CAND1, COPS5, CUL1, CUL3, CUL4B, SUMO1, DYRK2, TRA2B,
Protein Size: 392

Molekulargewicht: 43 kDa

Gen-ID: 27288

NCBI Accession: NM_014469, NP_055284

UniProt: O75526