RENT2/UPF2 Antikörper (N-Term)
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- Target Alle RENT2/UPF2 (UPF2) Antikörper anzeigen
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Ratte, Maus, Pferd, Schwein, Rind (Kuh), Saccharomyces cerevisiae, Zebrafisch (Danio rerio), Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RENT2/UPF2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KAPEDKKKRL EDDKRKKEDK ERKKKDEEKV KAEEESKKKE EEEKKKHQEE
- Homologie
- Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 86%, Yeast: 86%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against UPF2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human UPF2
- Top Product
- Discover our top product UPF2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1272 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
- Andere Bezeichnung
- UPF2 (UPF2 Produkte)
- Synonyme
- HUPF2 antikoerper, RENT2 antikoerper, smg-3 antikoerper, UPF2, regulator of nonsense mediated mRNA decay antikoerper, UPF2 regulator of nonsense transcripts homolog (yeast) antikoerper, UPF2 antikoerper, Upf2 antikoerper, upf2 antikoerper
- Hintergrund
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This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.
Alias Symbols: DKFZp434D222, HUPF2, KIAA1408, MGC138834, MGC138835, RENT2, smg-3
Protein Interaction Partner: PUF60, UBC, UPF1, LGR4, MIF, LDHA, KRT18, ITGB1, HMGA1, ZBTB48, HBZ, ENO1, E4F1, CYBA, CALR, BLM, ATP1B3, ART4, DCP1B, DCP2, COMTD1, EXOSC6, GADD45GIP1, ZGPAT, MAP1LC3B, ZNF408, CENPU, WNK1, RSRC2, MRPL40, ZNF44, EXOSC1, MTERF3, GLTSCR2, NOB1, RRP7A, SERB
Protein Size: 1272 - Molekulargewicht
- 148 kDa
- Gen-ID
- 26019
- NCBI Accession
- NM_015542, NP_056357
- UniProt
- Q9HAU5
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