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RNP Antikörper (Middle Region)

RNPC3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779114
  • Target Alle RNP (RNPC3) Antikörper anzeigen
    RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
    Bindungsspezifität
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Saccharomyces cerevisiae
    Wirt
    • 12
    • 3
    • 2
    Kaninchen
    Klonalität
    • 15
    • 2
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNP Antikörper ist unkonjugiert
    Applikation
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LHAPLPPTSP QPPEEPPLPD EDEELSSEES EYESTDDEDR QRMNKLMELA
    Homologie
    Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 92%, Rat: 85%, Yeast: 77%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RNPC3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RNPC3
    Top Product
    Discover our top product RNPC3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 517 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
    Andere Bezeichnung
    RNPC3 (RNPC3 Produkte)
    Synonyme
    rnp antikoerper, rbm40 antikoerper, zgc:136847 antikoerper, RBM40 antikoerper, RNP antikoerper, SNRNP65 antikoerper, 2810441O16Rik antikoerper, AI447568 antikoerper, C030014B17Rik antikoerper, RNA binding region (RNP1, RRM) containing 3 antikoerper, RNA-binding region (RNP1, RRM) containing 3 antikoerper, RNPC3 antikoerper, rnpc3 antikoerper, Rnpc3 antikoerper
    Hintergrund
    RNPC3 is an RNA-binding protein involved in pre-mRNA splicing. RNPC3 participates in pre-mRNA U12-dependent splicing. RNPC3 binds to the 3'-stem-loop of m7G-capped U12 snRNA.Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99 % of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
    Alias Symbols: FLJ20008, FLJ25070, KIAA183, RBM40, RNP
    Protein Interaction Partner: SMAD2, CPSF1, CDK19, RPS3A, APP, PRNP, RNU11, RNU12-2P,
    Protein Size: 517
    Molekulargewicht
    58 kDa
    Gen-ID
    55599
    NCBI Accession
    NM_017619, NP_060089
    UniProt
    Q96LT9
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