CDKN2AIP Antikörper (C-Term)

Produktnummer ABIN2779115

Produktdetails anti-CDKN2AIP Antikörper

Target: CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKN2AIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AIEALKATLD VFFVPLKELA DLPQNKSSQE SIVCELRCKS VYLGTGCGKS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CARF. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CARF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 580 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDKN2AIP

Target: CDKN2AIP (CDKN2A Interacting Protein (CDKN2AIP))

Andere Bezeichnung: CARF (CDKN2AIP Produkte)

Synonyme: CARF antikoerper, 4921511I16Rik antikoerper, AW208986 antikoerper, CDKN2AIP antikoerper, RGD1305302 antikoerper, CDKN2A interacting protein antikoerper, CDKN2A interacting protein L homeolog antikoerper, CDKN2AIP antikoerper, Cdkn2aip antikoerper, cdkn2aip antikoerper, cdkn2aip.L antikoerper

Hintergrund: CARF was first cloned as a novel binding partner of ARF from a yeast-interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2.
Alias Symbols: CARF
Protein Interaction Partner: UBC, XRN2, RPA3, RPA2, RPA1, WHSC1, VCP, Cdkn2a, MDC1, BRCA1, BARD1, GGH, EPHX1, MDM2, CUL3, SUMO2, RAD21, DHX58, Clp1,
Protein Size: 580

Molekulargewicht: 64 kDa

Gen-ID: 55602

NCBI Accession: NM_017632, NP_060102

UniProt: Q9NXV6