RG9MTD1 Antikörper (Middle Region)

Produktnummer ABIN2779118

Produktdetails anti-RG9MTD1 Antikörper

Target: RG9MTD1 (RNA (Guanine-9-) Methyltransferase Domain Containing 1 (RG9MTD1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Kaninchen, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RG9MTD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MKRKELQNTV SQLLESEGWN RRNVDPFHIY FCNLKIDGAL HRELVKRYQE

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against RG9MTD1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RG9MTD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 403 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RG9MTD1 Antikörper (ABIN2779118)

Szczepanowska, Maiti, Kukat, Hofsetz, Nolte, Senft, Becker, Ruzzenente, Hornig-Do, Wibom, Wiesner, Krüger, Trifunovic: "CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels." in: The EMBO journal, Vol. 35, Issue 23, pp. 2566-2583, (2016) (PubMed).

Details zu RG9MTD1

Target: RG9MTD1 (RNA (Guanine-9-) Methyltransferase Domain Containing 1 (RG9MTD1))

Andere Bezeichnung: RG9MTD1 (RG9MTD1 Produkte)

Hintergrund: RG9MTD1 functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends.
Alias Symbols: FLJ20432, MRPP1, RG9MTD1
Protein Interaction Partner: CEP76, CEP57, TP53, SUMO2, SUMO3, GRSF1, UBC, ASB1, UBD, CAND1, CUL3, HDGF, USP39,
Protein Size: 403

Molekulargewicht: 47 kDa

Gen-ID: 54931

NCBI Accession: NM_017819, NP_060289

UniProt: Q7L0Y3