CBX4 Antikörper (N-Term)

Produktnummer ABIN2779230

Produktdetails anti-CBX4 Antikörper

Target: CBX4 (Chromobox Homolog 4 (CBX4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LLIAFQNRER QEQLMGYRKR GPKPKPLVVQ VPTFARRSNV LTGLQDSSTD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against CBX4. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CBX4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 560 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CBX4 Antikörper (ABIN2779230)

Hao, Midic, Garriga, Latham: "Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos." in: Physiological genomics, Vol. 46, Issue 2, pp. 66-80, (2014) (PubMed).

Details zu CBX4

Target: CBX4 (Chromobox Homolog 4 (CBX4))

Andere Bezeichnung: CBX4 (CBX4 Produkte)

Synonyme: MPc2 antikoerper, PC2 antikoerper, NBP16 antikoerper, XPolycomb antikoerper, cbx4-a antikoerper, im:6911625 antikoerper, zgc:158588 antikoerper, chromobox 4 antikoerper, chromobox 4 S homeolog antikoerper, chromobox homolog 4 antikoerper, chromobox homolog 4 (Pc class homolog, Drosophila) antikoerper, CBX4 antikoerper, Cbx4 antikoerper, cbx4.S antikoerper, cbx4 antikoerper

Hintergrund: The polycomb group (PcG) protein HPC2, which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. Pc2 dramatically enhances CtBP sumoylation. Pc2 is a SUMO E3, and Polycomb Group bodies may be sumoylation centers.
Alias Symbols: PC2, NBP16
Protein Interaction Partner: Rnf111, SUMO1, NEDD8, CBS, BMI1, EED, RNF2, HECW2, SOX2, YWHAE, YWHAB, CCDC158, DIS3L2, HIST4H4, CBX2, PARP12, RNF213, ZKSCAN7, DCAF6, KDM3A, MYCBP2, ANKRD26, PSME3, TRANK1, CBX4, HIST1H2AB, YWHAZ, SKIL, NPM1, HIST1H2BB, GTF2I, PHC2, CSNK2B, CSNK2A2, CSNK
Protein Size: 560

Molekulargewicht: 61 kDa

Gen-ID: 8535

NCBI Accession: NM_003655, NP_003646