GLIS2 Antikörper (N-Term)

Produktnummer ABIN2779249

Produktdetails anti-GLIS2 Antikörper

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLIS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QDLVDHVNDY HVKPEKDAGY CCHWEGCARH GRGFNARYKM LIHIRTHTNE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GLIS2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLIS2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 524 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GLIS2 Antikörper (ABIN2779249)

Attanasio, Uhlenhaut, Sousa, OToole, Otto, Anlag, Klugmann, Treier, Helou, Sayer, Seelow, Nürnberg, Becker, Chudley, Nürnberg, Hildebrandt, Treier: "Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis." in: Nature genetics, Vol. 39, Issue 8, pp. 1018-24, (2007) (PubMed).

Details zu GLIS2

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Andere Bezeichnung: GLIS2 (GLIS2 Produkte)

Synonyme: glis2b antikoerper, nkl-A antikoerper, xNKLb antikoerper, NKL antikoerper, NPHP7 antikoerper, Gli5 antikoerper, Klf16 antikoerper, Nkl antikoerper, glis2a antikoerper, nphp7 antikoerper, GLIS family zinc finger 2 L homeolog antikoerper, GLIS family zinc finger 2 antikoerper, GLIS family zinc finger 2 S homeolog antikoerper, glis2.L antikoerper, GLIS2 antikoerper, Glis2 antikoerper, glis2.S antikoerper

Hintergrund: Members of the Kruppel-like zinc finger protein family, such as GLIS2, function as activators and/or repressors of gene transcription.
Alias Symbols: NKL, NPHP7
Protein Interaction Partner: TRIM32, UBC, PML, BBS2, BBS1, WNK1, XAB2, GPSM2, CPSF1, RBFOX2, SPECC1L, U2AF2, CTNNB1,
Protein Size: 524

Molekulargewicht: 56 kDa

Gen-ID: 84662

NCBI Accession: NM_032575, NP_115964

UniProt: Q9BZE0