MXD3 Antikörper (N-Term)

Produktnummer ABIN2779271

Produktdetails anti-MXD3 Antikörper

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Hund, Ratte, Rind (Kuh), Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MXD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PIHRRKKRPP QAPGAQDSGR SVHNELEKRR RAQLKRCLER LKQQMPLGAD

Homologie: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MXD3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 206 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MXD3 Antikörper (ABIN2779271)

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Details zu MXD3

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Andere Bezeichnung: MXD3 (MXD3 Produkte)

Synonyme: Mad3 antikoerper, BHLHC13 antikoerper, MAD3 antikoerper, MYX antikoerper, 4631412E13Rik antikoerper, bHLHc13 antikoerper, Mad antikoerper, zgc:66281 antikoerper, Myx antikoerper, MAX dimerization protein 3 antikoerper, Max dimerization protein 3 antikoerper, MAX dimerization protein 3 L homeolog antikoerper, mxd3 antikoerper, MXD3 antikoerper, Mxd3 antikoerper, mxd3.L antikoerper

Hintergrund: MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Alias Symbols: MYX, MAD3, BHLHC13
Protein Interaction Partner: NOTCH2NL, KRTAP10-7, UBC, NFKB1, MAGEA11, MAX, SIN3A, SMC3,
Protein Size: 206

Molekulargewicht: 23 kDa

Gen-ID: 83463

NCBI Accession: NM_031300, NP_112590

UniProt: Q9BW11