GFI1B Antikörper (N-Term)

Produktnummer ABIN2779273

Produktdetails anti-GFI1B Antikörper

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFI1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MPRSFLVKSK MAHTYHQPRV QEDEPLWPPA LTPVPRDQAP SNSPVLSTLF

Homologie: Cow: 83%, Dog: 100%, Goat: 83%, Horse: 100%, Human: 100%, Mouse: 83%, Pig: 93%, Rat: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against GFI1B. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GFI1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 330 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GFI1B

Target: GFI1B (Growth Factor Independent 1B Transcription Repressor (GFI1B))

Andere Bezeichnung: GFI1B (GFI1B Produkte)

Synonyme: GFI1B antikoerper, GFI antikoerper, znf544 antikoerper, MGC80648 antikoerper, Gfi-1B antikoerper, growth factor independent 1B transcriptional repressor antikoerper, growth factor independent 1B transcription repressor L homeolog antikoerper, Zinc finger protein Gfi-1b antikoerper, growth factor independent 1B antikoerper, GFI1B antikoerper, Gfi1b antikoerper, gfi1b.L antikoerper, gfi1b antikoerper

Hintergrund: GFI1B acts in the late stage of erythroid differentiation as a transcriptional repressor. GATA-1 and NF-Y both contribute to erythroid-specific transcriptional activation of the Gfi-1B promoter. This zinc finger protein mediates erythroid expansion and has a role in normal erythropoiesis.
Protein Interaction Partner: ZNRD1, EFEMP2, NSMF, IFFO1, RCHY1, TENC1, HECW1, MID2, CCDC85B, COPS5, RUNDC3A, PDLIM5, FBLN5, MATR3, PDE4DIP, BRE, PICK1, HGS, DNAJA3, KALRN, BECN1, LTBP4, VSNL1, TRIP6, TRAF1, TMF1, TAF1, ATXN2, TRIM27, PSMA3, NOTCH1, NELL2, NELL1, LAMB1, JAG2, HSPG2, H
Protein Size: 330

Molekulargewicht: 38 kDa

Gen-ID: 8328

NCBI Accession: NM_004188, NP_004179

UniProt: Q5VTD9

Pathways: Cellular Response to Molecule of Bacterial Origin