CLK4 Antikörper (N-Term)

Produktnummer ABIN2779361

Produktdetails anti-CLK4 Antikörper

Target: CLK4 (CDC-Like Kinase 4 (CLK4))

Bindungsspezifität: N-Term

Reaktivität: Maus, Human, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Pferd, Ratte, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RSRRSSPKRK RNRHCSSHQS RSKSHRRKRS RSIEDDEEGH LICQSGDVLR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against CLK4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 481 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CLK4 Antikörper (ABIN2779361)

Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

Details zu CLK4

Target: CLK4 (CDC-Like Kinase 4 (CLK4))

Andere Bezeichnung: CLK4 (CLK4 Produkte)

Synonyme: AI987988 antikoerper, C85119 antikoerper, zgc:112975 antikoerper, CDC like kinase 4 antikoerper, CDC-like kinase 4 antikoerper, CDC-like kinase 4b antikoerper, CLK4 antikoerper, Clk4 antikoerper, clk4b antikoerper

Hintergrund: The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
Alias Symbols: DKFZp686A20267
Protein Interaction Partner: KPNA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, CLK4, SRRM2, AHCYL2, SUB1, RASA4, SRPK1, RNF181, CLASRP, UBL5, HSPB2,
Protein Size: 481

Molekulargewicht: 57 kDa

Gen-ID: 57396

NCBI Accession: NM_020666, NP_065717

UniProt: Q9HAZ1