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NK2 Homeobox 5 Antikörper (N-Term)

NKX2-5 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779388
  • Target Alle NK2 Homeobox 5 (NKX2-5) Antikörper anzeigen
    NK2 Homeobox 5 (NKX2-5)
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 40
    • 19
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd
    Wirt
    • 42
    • 7
    • 1
    Kaninchen
    Klonalität
    • 44
    • 6
    Polyklonal
    Konjugat
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser NK2 Homeobox 5 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 30
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    ELGRAPSPAK CASAFPAAPA FYPRAYSDPD PAKDPRAEKK ELCALQKAVE
    Homologie
    Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 77%, Human: 100%, Mouse: 92%, Rabbit: 77%, Rat: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against NKX2-5. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the n terminal region of human Nkx2-5
    Top Product
    Discover our top product NKX2-5 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 324 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NK2 Homeobox 5 (NKX2-5)
    Andere Bezeichnung
    Nkx2-5 (NKX2-5 Produkte)
    Synonyme
    CHNG5 antikoerper, CSX antikoerper, CSX1 antikoerper, HLHS2 antikoerper, NKX2.5 antikoerper, NKX2E antikoerper, NKX4-1 antikoerper, VSD3 antikoerper, Csx antikoerper, Nkx-2.5 antikoerper, Nkx2.5 antikoerper, tinman antikoerper, nk2.5 antikoerper, nkx2-5 antikoerper, zgc:111912 antikoerper, AR2 antikoerper, XNkx2-5 antikoerper, csx antikoerper, nkx-2.5 antikoerper, nkx2-5b antikoerper, nkx2.5 antikoerper, NKX2-5 antikoerper, Nkx2-5 antikoerper, csx1 antikoerper, nkx2e antikoerper, XNkx-2.5 antikoerper, CNKX-2.5 antikoerper, NKX-2.5 antikoerper, NK2 homeobox 5 antikoerper, NK2 homeobox 5 S homeolog antikoerper, NKX2-5 antikoerper, Nkx2-5 antikoerper, nkx2.5 antikoerper, nkx2-5.S antikoerper, nkx2-5 antikoerper
    Hintergrund
    Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1211 U34962.1 1-1211 1212-1585 BC025711.1 1143-1516
    Alias Symbols: CSX, CSX1, NKX2.5, NKX2E, NKX4-1, VSD3, CHNG5, HLHS2
    Protein Interaction Partner: JARID2, GATA4, KDM6A, SMAD4, CAMTA2, TLE1, HDAC1, ID3, ID2, ID1, HIPK1, HIPK2, FOXH1, TBX5, TBX2, SRF, CSNK2A1,
    Protein Size: 324
    Molekulargewicht
    35 kDa
    Gen-ID
    1482
    NCBI Accession
    NM_004387, NP_004378
    UniProt
    P52952
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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