DVL2 Antikörper (N-Term)

Produktnummer ABIN2779458

Produktdetails anti-DVL2 Antikörper

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DVL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AGSSTGGGGV GETKVIYHLD EEETPYLVKI PVPAERITLG DFKSVLQRPA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DVL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DVL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 736 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DVL2 Antikörper (ABIN2779458)

Lee, Zhao, Moon, Yoon, Kim, An, Kwon, Hwang, Choi, Shim, Kim, Yang: "Differential involvement of GABA system in mediating behavioral and neurochemical effect of acupuncture in ethanol-withdrawn rats." in: Neuroscience letters, Vol. 443, Issue 3, pp. 213-7, (2008) (PubMed).

Details zu DVL2

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Andere Bezeichnung: DVL2 (DVL2 Produkte)

Synonyme: Xdsh antikoerper, dishevelled antikoerper, dsh antikoerper, dvl antikoerper, Dvl-2 antikoerper, xdsh antikoerper, wu:fc05d12 antikoerper, wu:fo71e09 antikoerper, wu:fp54a02 antikoerper, zgc:55372 antikoerper, dishevelled segment polarity protein 2 antikoerper, dishevelled segment polarity protein 2 L homeolog antikoerper, DVL2 antikoerper, dvl2 antikoerper, Dvl2 antikoerper, dvl2.L antikoerper

Hintergrund: DVL2 is a member of the dishevelled (dsh) protein family. It is a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, NUMA1, IQGAP1, DVL3, DVL1, RNF185, WWOX, SQSTM1, IRS2, IRS1, TARS, GABARAPL1, CSNK1E, OTULIN, TP53, LYN, Smurf2, PLA2G12A, CTBP2, LRRK2, ATN1, RBFOX1, ITCH, ELAVL1, NHLRC1, MAP1LC3A, GABARAP, VHL, SIRT1, VANGL1, TCEB3B, CPSF7, SNF8, PPM1A, POLI, DYNL
Protein Size: 736

Molekulargewicht: 79 kDa

Gen-ID: 1856

NCBI Accession: NM_004422, NP_004413

UniProt: O14641

Pathways: Tube Formation