SPIC Antikörper (C-Term)

Produktnummer ABIN2779513

Produktdetails anti-SPIC Antikörper

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Rind (Kuh), Pferd, Hund, Meerschweinchen, Ratte, Kaninchen, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPIC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EKLAELWGKR KGNRKTMTYQ KMARALRNYG RSGEITKIRR KLTYQFSEAI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against SPIC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 248 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SPIC Antikörper (ABIN2779513)

Zhu, Schweitzer, Romer, Sulentic, DeKoter: "Transgenic expression of Spi-C impairs B-cell development and function by affecting genes associated with BCR signaling." in: European journal of immunology, Vol. 38, Issue 9, pp. 2587-99, (2008) (PubMed).

Details zu SPIC

Target: SPIC (Spi-C Transcription Factor (Spi-1/PU.1 Related) (SPIC))

Andere Bezeichnung: SPIC (SPIC Produkte)

Synonyme: SPI-C antikoerper, AU019198 antikoerper, C76795 antikoerper, Prf antikoerper, Spi-C antikoerper, zgc:101790 antikoerper, spi-c antikoerper, spic antikoerper, Spi-C transcription factor antikoerper, transcription factor Spi-C-like antikoerper, Spi-C transcription factor (Spi-1/PU.1 related) antikoerper, Spi-C transcription factor (Spi-1/PU.1 related) S homeolog antikoerper, SPIC antikoerper, LOC100349167 antikoerper, Spic antikoerper, spic antikoerper, spic.S antikoerper

Hintergrund: SPIC controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. SPIC Regulates VCAM1 gene expression.
Alias Symbols: MGC40611, SPI-C
Protein Interaction Partner: APP,
Protein Size: 248

Molekulargewicht: 29 kDa

Gen-ID: 121599

NCBI Accession: NM_152323, NP_689536

UniProt: Q8N5J4