FOXF1 Antikörper (C-Term)

Produktnummer ABIN2779550

Produktdetails anti-FOXF1 Antikörper

Target: FOXF1 (Forkhead Box F1 (FOXF1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PCNPAANPLS GSLSTHSLEQ PYLHQNSHNA PAELQGIPRY HSQSPSMCDR

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXF1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 354 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOXF1 Antikörper (ABIN2779550)

Tamura, Sasaki, Koyama, Takeda, Idogawa, Tokino: "Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness." in: Oncogene, Vol. 33, Issue 40, pp. 4837-46, (2014) (PubMed).

Lo, Lee, Chen, Reisman, Berger, Sukumar: "Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas." in: Experimental and molecular pathology, Vol. 94, Issue 1, pp. 262-9, (2013) (PubMed).

Details zu FOXF1

Target: FOXF1 (Forkhead Box F1 (FOXF1))

Andere Bezeichnung: FOXF1 (FOXF1 Produkte)

Hintergrund: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in the regulation of pulmonary genes as well as embryonic development.
Alias Symbols: FKHL5, ACDMPV, FREAC1
Protein Size: 354

Molekulargewicht: 38 kDa

Gen-ID: 2294

NCBI Accession: NM_001451, NP_001442

UniProt: Q12946

Pathways: Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process