SCMH1 Antikörper (Middle Region)

Produktnummer ABIN2779551

Produktdetails anti-SCMH1 Antikörper

Target: SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Saccharomyces cerevisiae, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCMH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KTAEPLKFPK KRGPKPGSKR KPRTLLNPPP ASPTTSTPEP DTSTVPQDAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SCMH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SCMH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 591 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SCMH1

Target: SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))

Andere Bezeichnung: SCMH1 (SCMH1 Produkte)

Synonyme: Scml3 antikoerper, AI315320 antikoerper, AI851618 antikoerper, Scml1 antikoerper, zgc:162582 antikoerper, Scm polycomb group protein homolog 1 antikoerper, sex comb on midleg homolog 1 (Drosophila) antikoerper, sex comb on midleg homolog 1 antikoerper, Scm polycomb group protein homolog 1 L homeolog antikoerper, SCMH1 antikoerper, Scmh1 antikoerper, scmh1 antikoerper, scmh1.L antikoerper

Hintergrund: SCMH1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Alias Symbols: Scml3
Protein Interaction Partner: UBQLN1, RNF2, MAGEA12, BMI1, UBQLN4, PHC3, CBX4, PCGF2, PHC2, PHC1, MAML3, LZTR1, PCBD1, EWSR1, TMEM11, SCMH1, MOB4, TOB1, POLR2M, LYPLA2, GMNN, HK1, Cbx2,
Protein Size: 591

Molekulargewicht: 65 kDa

Gen-ID: 22955

NCBI Accession: NM_012236, NP_036368