EYA1 Antikörper (Middle Region)

Produktnummer ABIN2779640

Produktdetails anti-EYA1 Antikörper

Target: EYA1 (Eyes Absent Homolog 1 (EYA1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EYA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QDYPSYPSFG QGQYAQYYNS SPYPAHYMTS SNTSPTTPST NATYQLQEPP

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EYA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EYA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 557 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EYA1

Target: EYA1 (Eyes Absent Homolog 1 (EYA1))

Andere Bezeichnung: EYA1 (EYA1 Produkte)

Synonyme: EYA1 antikoerper, bop antikoerper, bor antikoerper, XEya1 antikoerper, wu:fc13c10 antikoerper, zgc:100770 antikoerper, BOP antikoerper, BOR antikoerper, BOS1 antikoerper, EYA transcriptional coactivator and phosphatase 1 antikoerper, EYA transcriptional coactivator and phosphatase 1 L homeolog antikoerper, EYA1 antikoerper, eya1 antikoerper, Eya1 antikoerper, eya1.L antikoerper

Hintergrund: EYA1 is a member of the eyes absent (EYA) family of proteins. EYA1 may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator.This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.
Alias Symbols: BOP, BOR, MGC141875
Protein Interaction Partner: GSK3B, FBXW7, UBC, FZR1, H2AFX, DACH1, SIX2, SIX3, SIX1, GNAI2, GNAZ,
Protein Size: 592

Molekulargewicht: 64 kDa

Gen-ID: 2138

NCBI Accession: NM_172060, NP_742057

UniProt: Q99502

Pathways: Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus