KAT2B Antikörper (N-Term)
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- Target Alle KAT2B Antikörper anzeigen
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KAT2B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LFKLLRKSIL QRGKPVVEGS LEKKPPFEKP SIEQGVNNFV QYKFSHLPAK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PCAF. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCAF
- Top Product
- Discover our top product KAT2B Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 832 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- Andere Bezeichnung
- PCAF (KAT2B Produkte)
- Synonyme
- PCAF antikoerper, pcaf antikoerper, si:ch211-1j13.2 antikoerper, zgc:161980 antikoerper, gb:dq017634 antikoerper, im:7156024 antikoerper, CAF antikoerper, P antikoerper, P/CAF antikoerper, A930006P13Rik antikoerper, AI461839 antikoerper, AW536563 antikoerper, Pcaf antikoerper, p/CAF antikoerper, lysine acetyltransferase 2B antikoerper, K(lysine) acetyltransferase 2B antikoerper, K(lysine) acetyltransferase 2A antikoerper, KAT2B antikoerper, kat2b antikoerper, kat2a antikoerper, Kat2b antikoerper
- Hintergrund
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CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Alias Symbols: P, CAF, PCAF, P/CAF
Protein Interaction Partner: MDM2, HNRNPD, ACLY, KLF2, E2F1, VHL, IRF1, TAL1, TAF12, TAF10, TAF9, TADA2A, RB1, HIST1H1B, TAF5L, TAF6L, TADA3, SUPT3H, TWIST1, PDK1, AKT1, UBC, SIAH2, UBE2D3, UBE2D1, TP73, TP53, SRC, PGR, YEATS2, MBIP, WDR5, PTEN, DR1, HIF1A, HIST2H3C, CHEK2, HIST1H4A,
Protein Size: 832 - Molekulargewicht
- 93 kDa
- Gen-ID
- 8850
- NCBI Accession
- NM_003884, NP_003875
- UniProt
- Q92831
- Pathways
- p53 Signalweg, Regulation of Carbohydrate Metabolic Process
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