EHMT2 Antikörper (N-Term)

Produktnummer ABIN2779680

Produktdetails anti-EHMT2 Antikörper

Target: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EHMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequenz: VQSLAMRLLS MPGAQGAAAA GSEPPPATTS PEGQPKVHRA RKTMSKPGNG

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 77%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EHMT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EHMT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1210 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EHMT2 Antikörper (ABIN2779680)

Kondo, Shen, Ahmed, Boumber, Sekido, Haddad, Issa: "Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells." in: PLoS ONE, Vol. 3, Issue 4, pp. e2037, (2008) (PubMed).

Details zu EHMT2

Target: EHMT2 (Ankyrin Repeat-Containing Protein (EHMT2))

Andere Bezeichnung: EHMT2 (EHMT2 Produkte)

Hintergrund: A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster, it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction.A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster, it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.
Alias Symbols: BAT8, C6orf30, DKFZp686H08213, FLJ35547, G9A, KMT1C, NG36, NG36/G9a, GAT8
Protein Interaction Partner: PLOD3, NAA10, PSMA1, MX2, ITGB5, RD3, ZBTB38, ZNF785, NAPRT, FAM161A, KLF3, CHCHD2, C10orf12, DNMT1, PML, HIST2H3A, HIST1H1A, PRDM1, XAGE2, EED, RNF2, CTNNA3, SOX2, HDAC1, CBX5, CBX3, CBX1, REST, EHMT1, WIZ, MIER1, EHMT2, CDYL, UBC, HDAC2, HIST2H3C, CUX1,
Protein Size: 1210

Molekulargewicht: 132 kDa

Gen-ID: 10919

NCBI Accession: NM_006709, NP_006700

UniProt: Q96KQ7