SUZ12 Antikörper (Middle Region)

Produktnummer ABIN2779689

Produktdetails anti-SUZ12 Antikörper

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUZ12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Sequenz: TGETNDKSTA PIAKPLATRN SESLHQENKP GSVKPTQTIA VKESLTTDLQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SUZ12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SUZ12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 739 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SUZ12

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Andere Bezeichnung: SUZ12 (SUZ12 Produkte)

Synonyme: fc31h10 antikoerper, im:7153578 antikoerper, si:dkey-10p5.2 antikoerper, suz12 antikoerper, wu:fc31h10 antikoerper, 2610028O16Rik antikoerper, AI195385 antikoerper, AU016842 antikoerper, AW536442 antikoerper, D11Ertd530e antikoerper, mKIAA0160 antikoerper, Xsuz12 antikoerper, chet9 antikoerper, jjaz1 antikoerper, CHET9 antikoerper, ChET 9 protein antikoerper, JJAZ1 antikoerper, suz12l antikoerper, zgc:100863 antikoerper, SUZ12 polycomb repressive complex 2b subunit antikoerper, SUZ12 polycomb repressive complex 2 subunit antikoerper, suppressor of zeste 12 homolog (Drosophila) antikoerper, SUZ12 polycomb repressive complex 2 subunit S homeolog antikoerper, SUZ12 polycomb repressive complex 2a subunit antikoerper, suz12b antikoerper, Suz12 antikoerper, SUZ12 antikoerper, suz12.S antikoerper, suz12a antikoerper

Hintergrund: A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7,17)(p15,q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CHET9, JJAZ1, KIAA0160
Protein Interaction Partner: FBXW11, EZH2, BRCA1, CDK5RAP2, RBM22, LUC7L, NHP2, H2AFY2, C17orf85, NAT10, ATAD3A, HEATR1, PTCD3, CHCHD3, CDKAL1, DDX56, GDAP1, LUC7L3, SF3B6, LUC7L2, NOP58, LIMA1, CDC40, CRNKL1, HP1BP3, STOML2, TRA2A, RBM15B, REPIN1, PRPF19, AKAP8L, TBL2, DAZAP1, PHGDH
Protein Size: 739

Molekulargewicht: 83 kDa

Gen-ID: 23512

NCBI Accession: NM_015355, NP_056170

UniProt: Q15022