SND1 Antikörper (N-Term)

Produktnummer ABIN2779724

Produktdetails anti-SND1 Antikörper

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SND1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LPDYYLVTVM LSGIKCPTFR READGSETPE PFAAEAKFFT ESRLLQRDVQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SND1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SND1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 885 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SND1

Target: SND1 (Staphylococcal Nuclease Domain Containing Protein 1 (SND1))

Andere Bezeichnung: SND1 (SND1 Produkte)

Synonyme: P100 antikoerper, TDRD11 antikoerper, p100 antikoerper, AL033314 antikoerper, SND p102 antikoerper, snd1 antikoerper, tdrd11 antikoerper, SN4TDR antikoerper, fc27g10 antikoerper, p100L antikoerper, p100S antikoerper, wu:fc27g10 antikoerper, staphylococcal nuclease and tudor domain containing antikoerper, staphylococcal nuclease and tudor domain containing 1 antikoerper, staphylococcal nuclease and tudor domain containing protein 1 S homeolog antikoerper, SND1 antikoerper, Snd1 antikoerper, snd1.S antikoerper, snd1 antikoerper

Hintergrund: SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN)-like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery
Alias Symbols: p100, TDRD11
Protein Interaction Partner: HUWE1, RAPGEF2, UBC, SUMO2, MDM2, LIN28A, SHFM1, DDX3X, EIF3CL, RPL35, RPS27, RPS26, RPS16, RPS11, RPS9, RPS6, RPS3A, RPS2, RPL23A, HNRNPU, TARDBP, UBD, RNU4-1, RNU5A-1, RNU6-1, PRPF8, RNU2-1, RNU1-1, G3BP1, VCAM1, MAK, ITGA4, FN1, CSNK2A1, SSR3, SRSF3, R
Protein Size: 885

Molekulargewicht: 100 kDa

Gen-ID: 27044

NCBI Accession: NM_014390, NP_055205

UniProt: Q7KZF4