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FOXP1 Antikörper (N-Term)

FOXP1 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779725
  • Target Alle FOXP1 Antikörper anzeigen
    FOXP1 (Forkhead Box P1 (FOXP1))
    Bindungsspezifität
    • 16
    • 14
    • 13
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 76
    • 49
    • 25
    • 18
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen
    Wirt
    • 81
    • 13
    • 1
    Kaninchen
    Klonalität
    • 71
    • 23
    • 1
    Polyklonal
    Konjugat
    • 44
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FOXP1 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 39
    • 33
    • 31
    • 12
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    MIPTELQQLW KEVTSAHTAE ETTGNNHSSL DLTTTCVSSS APSKTSLI
    Homologie
    Cow: 92%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against FOXP1. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP1
    Top Product
    Discover our top product FOXP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 677 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tang, Becanovic, Desplats, Spencer, Hill, Connolly, Masliah, Leavitt, Thomas: "Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease." in: Human molecular genetics, Vol. 21, Issue 14, pp. 3097-111, (2012) (PubMed).

    Konstantoulas, Parmar, Li: "FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3." in: Journal of neurochemistry, Vol. 113, Issue 4, pp. 836-47, (2010) (PubMed).

    Jepsen, Gleiberman, Shi, Simon, Rosenfeld: "Cooperative regulation in development by SMRT and FOXP1." in: Genes & development, Vol. 22, Issue 6, pp. 740-5, (2008) (PubMed).

  • Target
    FOXP1 (Forkhead Box P1 (FOXP1))
    Andere Bezeichnung
    FOXP1 (FOXP1 Produkte)
    Synonyme
    12CC4 antikoerper, QRF1 antikoerper, hFKH1B antikoerper, 3110052D19Rik antikoerper, 4932443N09Rik antikoerper, AI461938 antikoerper, AW494214 antikoerper, foxp1 antikoerper, im:7139058 antikoerper, wu:fc83a06 antikoerper, FOXP1 antikoerper, MGC145686 antikoerper, 12cc4 antikoerper, fkh1b antikoerper, hspc215 antikoerper, qrf1 antikoerper, xlfoxp1 antikoerper, im:7146611 antikoerper, wu:fb97f01 antikoerper, zgc:154010 antikoerper, forkhead box P1 antikoerper, forkhead box P1b antikoerper, forkhead box P1 S homeolog antikoerper, forkhead box P1a antikoerper, FOXP1 antikoerper, Foxp1 antikoerper, foxp1b antikoerper, foxp1 antikoerper, foxp1.S antikoerper, foxp1a antikoerper
    Hintergrund
    FOXP1 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s).
    Alias Symbols: QRF1, 12CC4, hFKH1B, HSPC215
    Protein Interaction Partner: SUMO2, MYC, IL3RA, ELAVL1, NCOR2, GATAD2B, MTA1, FOXP1, FOXP4, FOXP2, CTBP1,
    Protein Size: 677
    Molekulargewicht
    75 kDa
    Gen-ID
    27086
    NCBI Accession
    NM_032682, NP_116071
    UniProt
    Q9H334
    Pathways
    Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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