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HIPK2 Antikörper (Middle Region)

HIPK2 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2779735
  • Target Alle HIPK2 Antikörper anzeigen
    HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))
    Bindungsspezifität
    • 8
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 51
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd
    Wirt
    • 46
    • 6
    Kaninchen
    Klonalität
    • 45
    • 7
    Polyklonal
    Konjugat
    • 28
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HIPK2 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 26
    • 16
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    MWSLGCVIAE LFLGWPLYPG ASEYDQIRYI SQTQGLPAEY LLSAGTKTTR
    Homologie
    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 87%
    Produktmerkmale
    This is a rabbit polyclonal antibody against HIPK2. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human HIPK2
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1198 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Upadhyay, Bhadauriya, Ganesh: "Heat shock modulates the subcellular localization, stability, and activity of HIPK2." in: Biochemical and biophysical research communications, Vol. 472, Issue 4, pp. 580-4, (2016) (PubMed).

    Steinmann, Schulte, Beck, Chachra, Bujnicki, Klempnauer: "v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300." in: Oncogene, Vol. 28, Issue 26, pp. 2446-55, (2009) (PubMed).

    Choi, Seo, Kim, Sung, Ahn, Park, Lee, Choi: "Ubiquitination and degradation of homeodomain-interacting protein kinase 2 by WD40 repeat/SOCS box protein WSB-1." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4682-9, (2008) (PubMed).

  • Target
    HIPK2 (Homeodomain Interacting Protein Kinase 2 (HIPK2))
    Andere Bezeichnung
    HIPK2 (HIPK2 Produkte)
    Synonyme
    HIPK2 antikoerper, cb1009 antikoerper, si:dkey-16j24.2 antikoerper, si:dkey-239k7.1 antikoerper, wu:fk56d12 antikoerper, pro0593 antikoerper, MGC146781 antikoerper, PRO0593 antikoerper, 1110014O20Rik antikoerper, B230339E18Rik antikoerper, Stank antikoerper, PKM antikoerper, homeodomain interacting protein kinase 2 antikoerper, serine/threonine kinase antikoerper, homeodomain interacting protein kinase 2 L homeolog antikoerper, HIPK2 antikoerper, Smp_000720 antikoerper, hipk2 antikoerper, hipk2.L antikoerper, Hipk2 antikoerper
    Hintergrund
    HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors.
    Alias Symbols: DKFZp686K02111, FLJ23711, PRO0593
    Protein Interaction Partner: UBC, TP53, SIAH2, XAF1, AATF, SUMO1, MDM2, AXIN1, SIAH1, MBP, DAXX, MKNK1, MECP2, ZBTB4, HIPK2, DCAF7, DYRK1B, MAP3K1, DYRK1A, FBXO3, CBX4, SUMO2, SUMO3, PML, PAX6, CHMP4B, SENP2, SENP1, UBE2I, HIST2H2BE, CXCL1, SIAH1P1, WSB1, MYBL2, MYBL1, NLK, MAP3K7, M
    Protein Size: 1198
    Molekulargewicht
    120 kDa
    Gen-ID
    28996
    NCBI Accession
    NM_022740, NP_073577
    UniProt
    Q9H2X6
    Pathways
    Zellzyklus
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