Metabotropic Glutamate Receptor 6 Antikörper (C-Term)

Produktnummer ABIN2779742

Produktdetails anti-Metabotropic Glutamate Receptor 6 Antikörper

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ITFSLTSLQV VGMIAWLGAR PPHSVIDYEE QRTVDPEQAR GVLKCDMSDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GRM6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GRM6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 877 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Metabotropic Glutamate Receptor 6

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Andere Bezeichnung: GRM6 (GRM6 Produkte)

Hintergrund: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. GRM6 is part of Group III which is linked to the inhibition of the cyclic AMP cascade.
Alias Symbols: mGlu6, CSNB1B, GPRC1F, MGLUR6
Protein Interaction Partner: GNAO1,
Protein Size: 877

Molekulargewicht: 95 kDa

Gen-ID: 2916

NCBI Accession: NM_000843, NP_000834

UniProt: O15303