HDAC2 Antikörper (C-Term)
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- Target Alle HDAC2 Antikörper anzeigen
- HDAC2 (Histone Deacetylase 2 (HDAC2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Hund, Schwein, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HDAC2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- EEFSDSEDEG EGGRRNVADH KKGAKKARIE EDKKETEDKK TDVKEEDKSK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%
- Produktmerkmale
- This is a rabbit polyclonal antibody against HDAC2. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC2
- Top Product
- Discover our top product HDAC2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 488 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HDAC2 (Histone Deacetylase 2 (HDAC2))
- Andere Bezeichnung
- HDAC2 (HDAC2 Produkte)
- Synonyme
- HD2 antikoerper, RPD3 antikoerper, YAF1 antikoerper, D10Wsu179e antikoerper, Yy1bp antikoerper, mRPD3 antikoerper, HISTONE DEACETYLASE antikoerper, T1N24.9 antikoerper, T1N24_9 antikoerper, histone deacetylase 2 antikoerper, histone deacetylase 2 antikoerper, histone deacetylase 2 S homeolog antikoerper, HDAC2 antikoerper, Hdac2 antikoerper, hdac2.S antikoerper, HDA2 antikoerper
- Hintergrund
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Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
Alias Symbols: HD2, RPD3, YAF1
Protein Interaction Partner: BRCA1, SUMO1, UBC, SMAD7, SMAD2, MXD1, NCOR2, SUMO2, SFPQ, KDM5A, HDAC1, DDB1, CUL4B, CHFR, KDM1A, KDM5B, NFE2L2, PRDM6, DNMT3B, DNMT1, NACC2, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, PRDM1, EED, RNF2, SP1, CHD4, CHD3, ACTL6A, C16orf87, HMG20A, HMG20B, C
Protein Size: 488 - Molekulargewicht
- 55 kDa
- Gen-ID
- 3066
- NCBI Accession
- NM_001527, NP_001518
- UniProt
- Q92769
- Pathways
- Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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