TRIM23 Antikörper (Middle Region)

Produktnummer ABIN2779792

Produktdetails anti-TRIM23 Antikörper

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Meerschweinchen, Pferd, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KHSVLEPEAN QIRASILDMA HCIRTFTEEI SDYSRKLVGI VQHIEGGEQI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIM23. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM23

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 546 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIM23

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Andere Bezeichnung: TRIM23 (TRIM23 Produkte)

Hintergrund: TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Alias Symbols: ARD1, ARFD1, RNF46
Protein Interaction Partner: LGALS8, TNFAIP3, TMSB4X, SNRPB, SNAI1, SNAI2, SIAH1, PSMA1, PIK3R2, PHF1, LMO2, FAM90A1, KRT6A, KIFC3, HOXB5, COX5B, CDR2, BAG1, TRIM23, AQP1, SLC25A6, FAM208B, FAM193B, ZNF581, SPG21, MRPL4, ARHGEF3, POLL, NFU1, GPKOW, HSPB7, PPIL2, TRIM29, DMC1, USP20,
Protein Size: 546

Molekulargewicht: 61 kDa

Gen-ID: 373

NCBI Accession: NM_033228, NP_150231