Mesp2 Antikörper (C-Term)

Produktnummer ABIN2779870

Produktdetails anti-Mesp2 Antikörper

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mesp2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SCQRLQPQPQ PQPQWGCWGH DAEVLSTSED QGSSPALQLP VASPTPSSGL

Homologie: Mouse: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against MESP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse MESP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 370 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Mesp2 Antikörper (ABIN2779870)

Leschik, Stefanovic, Brinon, Pucéat: "Cardiac commitment of primate embryonic stem cells." in: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, (2008) (PubMed).

Details zu Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Andere Bezeichnung: MESP2 (Mesp2 Produkte)

Synonyme: bHLHc6 antikoerper, SCDO2 antikoerper, mesoderm posterior 2 antikoerper, mesoderm posterior bHLH transcription factor 2 antikoerper, Mesp2 antikoerper, MESP2 antikoerper

Hintergrund: Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2.
Alias Symbols: bHLHc6
Protein Interaction Partner: Lfng,
Protein Size: 370

Molekulargewicht: 41 kDa

Gen-ID: 17293

NCBI Accession: NM_008589, NP_032615

UniProt: O08574