FIGLA Antikörper (C-Term)

Produktnummer ABIN2779982

Produktdetails anti-FIGLA Antikörper

Target: FIGLA (Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FIGLA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSTRELLGNA TQPTSCASGL KKEEEGPWAY AGHSEPLYSY HQSTVPETRS

Homologie: Mouse: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Figla. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Figla

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FIGLA

Target: FIGLA (Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))

Andere Bezeichnung: Figla (FIGLA Produkte)

Synonyme: bHLHc8 antikoerper, BHLHC8 antikoerper, FIGALPHA antikoerper, POF6 antikoerper, RGD1564754 antikoerper, bhlhc8 antikoerper, figalpha antikoerper, figla antikoerper, pof6 antikoerper, FIGalpha antikoerper, fig1a antikoerper, zgc:109752 antikoerper, folliculogenesis specific basic helix-loop-helix antikoerper, folliculogenesis specific bHLH transcription factor antikoerper, folliculogenesis specific bHLH transcription factor L homeolog antikoerper, Figla antikoerper, FIGLA antikoerper, figla.L antikoerper, figla antikoerper

Hintergrund: Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
Alias Symbols: bHLHc8
Protein Size: 194

Molekulargewicht: 21 kDa

Gen-ID: 26910

NCBI Accession: NM_012013, NP_036143

UniProt: O55208