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MCAF1 Antikörper (Middle Region)

ATF7IP Reaktivität: Schwein, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2780013
  • Target Alle MCAF1 (ATF7IP) Antikörper anzeigen
    MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
    Bindungsspezifität
    • 3
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    Schwein, Maus, Ratte
    Wirt
    • 6
    • 2
    Kaninchen
    Klonalität
    • 6
    • 2
    Polyklonal
    Konjugat
    • 8
    Dieser MCAF1 Antikörper ist unkonjugiert
    Applikation
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    MSTPEGEKSE KDGKAEEEER VPAEEQPPVR NEFSRRKRSK SEDMDSVESK
    Homologie
    Mouse: 100%, Pig: 92%, Rat: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against Atf7ip. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Mouse Atf7ip
    Top Product
    Discover our top product ATF7IP Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1306 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MCAF1 (ATF7IP) (Activating Transcription Factor 7 Interacting Protein (ATF7IP))
    Andere Bezeichnung
    Atf7ip (ATF7IP Produkte)
    Synonyme
    ATF7IP antikoerper, AM antikoerper, MCAF antikoerper, MCAF1 antikoerper, p621 antikoerper, 2610204M12Rik antikoerper, Mcaf1 antikoerper, fa12g02 antikoerper, wu:fa12g02 antikoerper, zgc:152981 antikoerper, activating transcription factor 7 interacting protein antikoerper, Atf7ip antikoerper, ATF7IP antikoerper, atf7ip antikoerper
    Hintergrund
    Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Atf7ip can both act as an activator or a repressor depending on the context. It mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Atf7ip is required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Atf7ip may have ATPase activity.
    Alias Symbols: 2610204M12Rik, AM, Mcaf1
    Protein Interaction Partner: Atf7, Gtf2f1, Gtf2e2, Aagab, Ccnh, Gtf2h1, Ercc3, Cdk7, C1qbp, POLR2H, POLR2G, POLR2D, POLR2C,
    Protein Size: 1306
    Molekulargewicht
    138 kDa
    Gen-ID
    54343
    NCBI Accession
    NM_019426, NP_062299
    UniProt
    Q7TT18
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