ISL2 Antikörper (C-Term)

Produktnummer ABIN2780062

Produktdetails anti-ISL2 Antikörper

Target: ISL2 (ISL LIM Homeobox 2 (ISL2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VIRVWFQNKR CKDKKKSILM KQLQQQQHSD KASFQGLTGT PLVAGSPIGH

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 86%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ISL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of mouse ISL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 359 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ISL2 Antikörper (ABIN2780062)

Svärd, Heby-Henricson, Henricson, Persson-Lek, Rozell, Lauth, Bergström, Ericson, Toftgård, Teglund: "Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway." in: Developmental cell, Vol. 10, Issue 2, pp. 187-97, (2006) (PubMed).

Details zu ISL2

Target: ISL2 (ISL LIM Homeobox 2 (ISL2))

Andere Bezeichnung: ISL2 (ISL2 Produkte)

Synonyme: ISL-2 antikoerper, isl2 antikoerper, wu:fc29g02 antikoerper, zfIsl-2 antikoerper, ISLET-2 antikoerper, ISL-3 antikoerper, isl3 antikoerper, islet 3 antikoerper, zfIsl-3 antikoerper, zgc:109840 antikoerper, ISL LIM homeobox 2 antikoerper, ISL LIM homeobox 2a antikoerper, ISL LIM homeobox 2b antikoerper, ISL2 antikoerper, Isl2 antikoerper, isl2a antikoerper, isl2b antikoerper

Hintergrund: Isl2 specifies RGC laterality by repressing an ipsilateral pathfinding program unique to VTC RGCs and involving Zic2 and EphB1. This genetic hierarchy controls binocular vision.
Alias Symbols: 3110001N10Rik
Protein Interaction Partner: Zfp446, Ssbp4, Ssbp3, Pygo1, Ssbp2, Lhx4, Ldb2, Ldb1,
Protein Size: 359

Molekulargewicht: 39 kDa

Gen-ID: 104360

NCBI Accession: NM_027397, NP_081673

UniProt: Q9CXV0