MAFA Antikörper (C-Term)
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- Target Alle MAFA Antikörper anzeigen
- MAFA (Transcription Factor MafA (MAFA))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAFA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KLEVGRLAKE RDLYKEKYEK LAGRGGPGGA GGAGFPREPS PAQAGPGAAK
- Homologie
- Human: 86%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Mafa. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product MAFA Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 359 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MAFA (Transcription Factor MafA (MAFA))
- Andere Bezeichnung
- Mafa (MAFA Produkte)
- Synonyme
- RIPE3b1 antikoerper, hMafA antikoerper, RGD1562627 antikoerper, 2F1-Ag antikoerper, MAFA antikoerper, MAFA-L antikoerper, SMaf1 antikoerper, mafl antikoerper, L-MAF antikoerper, MAFL antikoerper, Maf antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antikoerper, MAF bZIP transcription factor A antikoerper, killer cell lectin-like receptor subfamily G, member 1 antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antikoerper, monocyte to macrophage differentiation-associated antikoerper, Mafa antikoerper, MAFA antikoerper, Klrg1 antikoerper, mafa antikoerper, mafaa antikoerper, Mmd antikoerper
- Hintergrund
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Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: RIPE3b1
Protein Interaction Partner: Psme3,
Protein Size: 359 - Molekulargewicht
- 37 kDa
- Gen-ID
- 378435
- NCBI Accession
- NM_194350, NP_919331
- UniProt
- Q8CF90
- Pathways
- Hormone Transport
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